Marvel Puzzle Quest

The story involves a powerful new substance called Iso-8 and Norman Osborn's attempts to supplant S.H.I.E.L.D. There are five missions to stop Osborn on his worldwide terror spree. The original story is based on the Dark Reign storyline and was written by Frank Tieri and Alex Irvine. Irvine also wrote other player versus environment events of the game, such as “Webbed Wonder,” where Spider-Man teams up with Howard the Duck to find out Aunt May's whereabouts.